Vol. 25 (2026)

Original articles

Comparison of LDH activity and LDH-M to predict death in patients with acetaminophen-induced acute liver failure

Debasree Bhadra, Jody A. Rule, William M. Lee, Mitchell R. McGill

330-338
- Article - PDF
Long-term Western diet feeding impairs hepatic vitamin D metabolism and promotes bone loss in mice

Pengcheng Zhou, Mohammad Majd Hammour, Romina H. Aspera-Werz, Sabrina Ehnert, Maiju Myllys, Zaynab Hobloss, Reham Hassan, Daniela González, Rama Hendawi, Karolina Edlund, Sandra Hans, Matthias W. Laschke, Ahmed Ghallab, Jan G. Hengstler, Andreas Nüssler, Tanja C. Maisenbacher

290-309
- Article - PDF
Candesartan cilexetil as a repurposed therapeutic candidate for nasopharyngeal carcinoma: Integrated in vitro and in silico analyses

Chawalit Ngernsombat, Utid Suriya, Somsiri Udompaisarn, Natta Panomchoeng, Tavan Janvilisri

204-221
- Article - PDF
Real-world data of tirzepatide in obesity management: a multicenter study by the Italian Society of Obesity – Campania Region

Luigi Barrea, Ludovica Verde, Martina Galasso, Renato Patrone, Lucia Digitale, Alessandro Limardi, Marcello Orio, Giovanni Ragozzino, Luigi Digitale, Vittorio Salvatore, Antonella Savoia, Silvia Savastano, Annamaria Colao, Giovanna Muscogiuri

191-203
- Article - PDF
A cross-sectional exploratory study of rat sarcoma (Ras) activation in non-obese women with and without polycystic ovary syndrome

Sara Anjum Niinuma, Haniya Habib, Ashleigh Suzu-Nishio Takemoto, Thozhukat Sathyapalan, Stephen L. Atkin, Alexandra E. Butler

174-185
- Article - PDF
RNA-Seq-based investigation of interferon-mediated antiviral activity of chlorophyll a from Tetraselmis sp.

Nalae Kang, Eun-A. Kim, Yeon-Ji Lee, Seong-Yeong Heo, Jun-Ho Heo, Won-Kyu Lee, Yong-Kyun Ryu, Taeho Kim, Soo-Jin Heo

150-166
- Article - PDF
Neurotoxicity of mancozeb-based commercial fungicide in human neuroblastoma SH-SY5Y cells

Evelin G. Cuadros-Buenaventura, Lenin Javier Ramírez-Cando, Ronny Alexander Ordoñez Sánchez, Johnny Chimborazo, Santiago Ballaz

133-149
- Article - PDF
Metabolic profiling reveals potential biomarkers and underlying signaling pathways involved in mindfulness-based cognitive therapy-improved adolescent depression symptoms

Chun-Hua Xu, Bi-Lan Zhang, Chun-Lan Guan, Lin Wang, Shan Chao, He Li, Qiu-Ping Wu, Da-Jin Zhou, Guo-Qing Min, Fan Yang

68-101
- Article - PDF
Methyl linolenate suppresses the growth and proliferation of Ehrlich ascites carcinoma (EAC) cells by inducing intrinsic mitochondrial apoptosis

Azmin Akter, Tasnima Kamal, M. Matakabbir Hossain, Abdul Auwal, Khan Mohammad Rashel, Tasfik Ul Haque Pronoy, Asmaulhusna Biswas, Sharmin Akter, Mahmud Ismail, M. Rowshanul Habib, Farhadul Islam

50-67
- Article - PDF
Computational analysis of hub genes associated with sarcopenia: integrative transcriptome insights from an Asian cohort

Jae Gyu Kim, Ashish Ranjan Sharma, Yeon-Hee Lee, Min-Jee Kwon, Chiranjib Chakraborty, Jin-Chul Kim, Holger Jahr, Sang-Soo Lee

18-34
- Article - PDF
IL-8 and follicular fluid: insights into the mechanisms of endometriosis development

Anne Teresa Heinrich, Ada Leoni Terres-Wurtz, Elisa Vacca, Katrin E. Tagscherer, Bartosz Linek, Susanne Gebhard, Annette Hasenburg, Walburgis Brenner, Roxana Schwab

1-17
- Article - PDF

Review articles

Efficacy and safety of CTLA-4, PD-1 and LAG-3 immune checkpoint inhibitors as monotherapy and combination therapy in advanced melanoma: A systematic review and meta-analysis

Osama Omar Khan

310-329
- Article - PDF
Bridging pathologies: Mechanistic insights into the diabetes–Alzheimer's nexus

Aniket Kakkar, Harpreet Singh, Yash Jasoria, Arvind Kumar, Shivani Chopra, Hitesh Chopra, Arun Kumar Mishra

261-289
- Article - PDF
Epigenetic regulation of PANoptosis: DNA methylation, histone modifications and non-coding RNAs

Yogendra Singh, Muhammad Afzal, M. Arockia Babu, Surya Nath Pandey, Arcot Rekha, Gaurav Gupta, Imran Kazmi, Sami I. Alzarea, Omar Awad Alsaidan, Waleed Hassan Almalki, Salem Salman Almujri

238-260
- Article - PDF
Eugenol: A promising therapeutic terpenoid against ischemia-reperfusion injury

Puneet Kaur Randhawa, Deepti Gupta, Mohd Hanifa, Bivek Bajgai, Sorabh Sehajpal, Sarbeshwar Jaggi, Anjana Bali

222-237
- Article - PDF
Development of nanoparticle-based Toll-like receptor agonists for respiratory immunotherapy

Amisha S. Raikar, Ananya Verma, Mayuri B. Naik, Sweta M. Prabhu, Keshav Raj Paudel, Kamal Dua

102-130
- Article - PDF

Case reports

The hidden path of mycobacterium: a case series of rare and elusive manifestations of gastrointestinal tuberculosis

Nitika Yadav, Abhishek Yadav, Neharica Joshi, Shubhangi Gupta, Yashendra Sethi

35-49
- Article - PDF

Letters to the editor

Acetylsalicylic acid versus clopidogrel in cardiovascular prevention: Does the classic still outperform the contemporary?

Ian Jhemes Oliveira Sousa, Kerolayne de Melo Nogueira

342-344
- Article - PDF
Beyond the pitch: The unaddressed challenges of inadequate uniforms in women's football

Rizia Rocha-Silva, Geovana José, Marília Santos Andrade, Claudio Andre Barbosa de Lira

339-341
- Article - PDF
On the prenatal origins of the myeloproliferative neoplasms

Stephen E. Langabeer

189-190
- Article - PDF
Ethnicity matters: The case for regional reference intervals in polycystic ovary syndrome (PCOS) diagnostics

Pallav Sengupta, Sulagna Dutta

186-188
- Article - PDF
Redefining the role of exercise: beyond medicine and polypill

Kayvan Khoramipour, Susana López-Ortiz, Alejandro Santos-Lozano

170-173
- Article - PDF
Semaglutide and tirzepatide: Oral cavity effects of weight-loss therapies

Maria Eduarda Bernardo, Felipe Gomes Dallepiane, Mario Escobar, Ariadne Cristiane Cabral Cruz, Cesar Augusto Magalhães Benfatti

167-169
- Article - PDF
Why does the world continue to struggle with effectively addressing hepatitis E?

Henrique Borges da Silva Grisard, Gislaine Fongaro

131-132
- Article - PDF

Original articles

Comparison of LDH activity and LDH-M to predict death in patients with acetaminophen-induced acute liver failure

Long-term Western diet feeding impairs hepatic vitamin D metabolism and promotes bone loss in mice

Candesartan cilexetil as a repurposed therapeutic candidate for nasopharyngeal carcinoma: Integrated in vitro and in silico analyses

Real-world data of tirzepatide in obesity management: a multicenter study by the Italian Society of Obesity – Campania Region

A cross-sectional exploratory study of rat sarcoma (Ras) activation in non-obese women with and without polycystic ovary syndrome

RNA-Seq-based investigation of interferon-mediated antiviral activity of chlorophyll a from Tetraselmis sp.

Neurotoxicity of mancozeb-based commercial fungicide in human neuroblastoma SH-SY5Y cells

Metabolic profiling reveals potential biomarkers and underlying signaling pathways involved in mindfulness-based cognitive therapy-improved adolescent depression symptoms

Methyl linolenate suppresses the growth and proliferation of Ehrlich ascites carcinoma (EAC) cells by inducing intrinsic mitochondrial apoptosis

Computational analysis of hub genes associated with sarcopenia: integrative transcriptome insights from an Asian cohort

IL-8 and follicular fluid: insights into the mechanisms of endometriosis development

Review articles

Efficacy and safety of CTLA-4, PD-1 and LAG-3 immune checkpoint inhibitors as monotherapy and combination therapy in advanced melanoma: A systematic review and meta-analysis

Bridging pathologies: Mechanistic insights into the diabetes–Alzheimer's nexus

Epigenetic regulation of PANoptosis: DNA methylation, histone modifications and non-coding RNAs

Eugenol: A promising therapeutic terpenoid against ischemia-reperfusion injury

Development of nanoparticle-based Toll-like receptor agonists for respiratory immunotherapy

Case reports

The hidden path of mycobacterium: a case series of rare and elusive manifestations of gastrointestinal tuberculosis

Letters to the editor

Acetylsalicylic acid versus clopidogrel in cardiovascular prevention: Does the classic still outperform the contemporary?

Beyond the pitch: The unaddressed challenges of inadequate uniforms in women's football

On the prenatal origins of the myeloproliferative neoplasms

Ethnicity matters: The case for regional reference intervals in polycystic ovary syndrome (PCOS) diagnostics

Redefining the role of exercise: beyond medicine and polypill

Semaglutide and tirzepatide: Oral cavity effects of weight-loss therapies

Why does the world continue to struggle with effectively addressing hepatitis E?

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