The role of magnesium sulfate in the intensive care unit

Authors

  • Yunes Panahi Clinical Pharmacy Department, Faculty of Pharmacy, Baqiyatallah University of Medical Sciences, Tehran, Iran; Clinical Pharmacy Department, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  • Mojtaba Mojtahedzadeh Clinical Pharmacy Department, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran; Research Center for Rational Use of Drugs, Tehran University of Medical Sciences, Tehran, Iran
  • Atabak Najafi Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
  • Mohammad Reza Ghaini Department of Neurosurgery and Neurology, Sina Hospital, Tehran University, Iran
  • Mohammad Abdollahi Department of Toxicology and Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  • Mohammad Sharifzadeh Department of Toxicology and Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  • Arezoo Ahmadi Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
  • Seyyed Mahdi Rajaee Clinical Pharmacy Department, Faculty of Pharmacy, Baqiyatallah University of Medical Sciences, Tehran, Iran
  • Amirhossein Sahebkar Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

DOI:

https://doi.org/10.17179/excli2017-182

Keywords:

magnesium sulfate, intensive care unit, neuroprotection, ICU

Abstract

Magnesium (Mg) has been developed as a drug with various clinical uses. Mg is a key cation in physiological processes, and the homeostasis of this cation is crucial for the normal function of body organs. Magnesium sulfate (MgSO4) is a mineral pharmaceutical preparation of magnesium that is used as a neuroprotective agent. One rationale for the frequent use of MgSO4 in critical care is the high incidence of hypomagnesaemia in intensive care unit (ICU) patients. Correction of hypomagnesaemia along with the neuroprotective properties of MgSO4 has generated a wide application for MgSO4 in ICU.

Published

2017-04-05

How to Cite

Panahi, Y., Mojtahedzadeh, M., Najafi, A., Ghaini, M. R., Abdollahi, M., Sharifzadeh, M., Ahmadi, A., Rajaee, S. M., & Sahebkar, A. (2017). The role of magnesium sulfate in the intensive care unit. EXCLI Journal, 16, 464–482. https://doi.org/10.17179/excli2017-182

Issue

Section

Review articles

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