Intraspecific differences in Androctunus crassicauda venom and envenomation symptoms

Authors

  • Mehdi Safdarian Nanotechnology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran https://orcid.org/0000-0001-9735-2632
  • Babak Vazirianzadeh Social Determinant of Health Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran https://orcid.org/0000-0002-0690-5981
  • Ahmad Ghorbani Toxicology Research Center, Medical Basic Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran https://orcid.org/0000-0001-9186-1508
  • Narges Pashmforoosh Toxicology Research Center, Medical Basic Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran https://orcid.org/0000-0002-4147-681X
  • Masoumeh Baradaran Toxicology Research Center, Medical Basic Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. E-mail: mb.baradaran@gmail.com https://orcid.org/0000-0003-2521-2344

DOI:

https://doi.org/10.17179/excli2022-5078

Keywords:

Androctunus crassicauda, intraspecific differences, envenomation symptoms, venom difference

Abstract

Envenomation by Androctunus crassicauda is very frequent in Iran, especially in the south-west. This scorpion is one of the six scorpions whose venom is used to prepare anti-venom. Using HPLC, we discovered venom components of A. crassicauda varies from one specimen to another depending on geographical location, and this result is confirmed by those first found in various symptoms of A. crassicauda sting in envenomed persons from two separate geographical places (north and south of Khuzestan province). There was a significant relationship between symptoms and location of envenomation by A. crassicauda. Muscle spasm was more dominant in envenomed people from Northern cities, and venom chromatogram analysis showed the presence of at least six main sharp peaks in Northern A. crassicauda rather than Southern A. crassicauda. It shows intraspecific differences in venom of A. crassicauda that must be considered in treatment of stung people from different geographical locations as well as in the preparation of anti-venom.

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Published

2022-09-21

How to Cite

Safdarian, M., Vazirianzadeh, B., Ghorbani, A., Pashmforoosh, N., & Baradaran, M. (2022). Intraspecific differences in Androctunus crassicauda venom and envenomation symptoms. EXCLI Journal, 21, 1222–1230. https://doi.org/10.17179/excli2022-5078

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