Particles from preformed polymers as carriers for drug delivery

Authors

  • K. Miladi University of Lyon, France; Lyon 1 University, Villeurbanne, CNRS, UMR 5007, Laboratoire d'Automatique et de Génie des Procédés, LAGEP-CPE-308G, Villeurbanne, France; University of Monastir, Laboratoire de pharmacie galénique, Rue Avicenne, 5000 Monastir, Tunisia
  • D. Ibraheem University of Lyon, France; Lyon 1 University, Villeurbanne, CNRS, UMR 5007, Laboratoire d'Automatique et de Génie des Procédés, LAGEP-CPE-308G, Villeurbanne, France
  • M. Iqbal University of Lyon, France; Lyon 1 University, Villeurbanne, CNRS, UMR 5007, Laboratoire d'Automatique et de Génie des Procédés, LAGEP-CPE-308G, Villeurbanne, France
  • S. Sfar University of Monastir, Laboratoire de pharmacie galénique, Rue Avicenne, 5000 Monastir, Tunisia
  • H. Fessi University of Lyon, France; Lyon 1 University, Villeurbanne, CNRS, UMR 5007, Laboratoire d'Automatique et de Génie des Procédés, LAGEP-CPE-308G, Villeurbanne, France
  • A. Elaissari University of Lyon, France; Lyon 1 University, Villeurbanne, CNRS, UMR 5007, Laboratoire d'Automatique et de Génie des Procédés, LAGEP-CPE-308G, Villeurbanne, France

Keywords:

drug delivery, particles, polymer, encapsulation, carriers, operating conditions

Abstract

Biodegradable and biocompatible polymers are widely used for the encapsulation of drug molecules. Various particulate carriers with different sizes and characteristics have been prepared by miscellaneous techniques. In this review, we reported the commonly used preformed polymer based techniques for the preparation of micro and nano-structured materials intended for drug encapsulation. A description of polymer-solvent interaction was provided. The most widely used polymers were reported and described and their related research studies were mentioned. Moreover, principles of each technique and its crucial operating conditions were described and discussed. Recent applications of all the reported techniques in drug delivery were also reviewed.

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Published

2014-02-03

How to Cite

Miladi, K., Ibraheem, D., Iqbal, M., Sfar, S., Fessi, H., & Elaissari, A. (2014). Particles from preformed polymers as carriers for drug delivery. EXCLI Journal, 13, 28–57. Retrieved from https://www.excli.de/index.php/excli/article/view/681

Issue

Vol. 13 (2014)

Section

Review articles

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