Combined anti-ages and antioxidant activities of different solvent extracts of Solanum elaeagnifolium Cav (Solanacea) fruits during ripening and related to their phytochemical compositions

Authors

  • Mejri Houda Laboratory of Bioactive Substances, Biotechnology Center, Technopark of Borj-Cedria, BP 901, 2050 Hammam-Lif, Tunisia; University of Angers, Laboratoire des Substances d’Origine Naturelle et Analogues Structuraux, SONAS-EA 921, IFR 149 QUASAV, 16 Bd Daviers, 49045 Angers, France
  • Séverine Derbré University of Angers, Laboratoire des Substances d’Origine Naturelle et Analogues Structuraux, SONAS-EA 921, IFR 149 QUASAV, 16 Bd Daviers, 49045 Angers, France
  • Ahmed Jedy Laboratory of Bioactive Substances, Biotechnology Center, Technopark of Borj-Cedria, BP 901, 2050 Hammam-Lif, Tunisia
  • Nizar Tlili Laboratoire de Biochimie, Département de Biologie, Faculté des Sciences de Tunis, Université Tunis El-Manar, Tunis 2092, Tunisie
  • Jean Legault Laboratory LASEVE, Université du Québec a Chicoutimi, 555 Boulevard de l’Université à Chicoutimi, Québec, Canada G7H 2B1
  • Pascal Richomme University of Angers, Laboratoire des Substances d’Origine Naturelle et Analogues Structuraux, SONAS-EA 921, IFR 149 QUASAV, 16 Bd Daviers, 49045 Angers, France
  • Ferid Limam Laboratory of Bioactive Substances, Biotechnology Center, Technopark of Borj-Cedria, BP 901, 2050 Hammam-Lif, Tunisia
  • Moufida Saidani-Tounsi Laboratory of Bioactive Substances, Biotechnology Center, Technopark of Borj-Cedria, BP 901, 2050 Hammam-Lif, Tunisia

Keywords:

Solanum elaeagnifolium Cav, advanced glycation endproduct (AGEs), in vitro and ex-vivo antioxidant activities, phenolic compounds

Abstract

Oxidative stress and advanced glycation end products (AGEs) are known as key factors for the development of diabetic complications such as retinopathy, cataract as well as atherosclerosis and neurodegenerative diseases, including Alzheimer’s diseases. In this context, natural products have been previously identified as promising sources for antioxidant and anti-glycation compounds. The current study focuses on the evaluation of antioxidant and glycation inhibitory activities of different solvent extracts of Solanum elaeagnifolium Cav (Solanaceae) fruits at different ripening stages. The results showed that antioxidant and anti-AGEs activities were significantly influenced by solvents polarities and ripening stages of S. elaeagnifolium Cav. With one exception, methanolic extract of overripe S. elaeagnifolium Cav fruit showed important protective effects against cellular oxidative stress. The aqueous extract showed the highest ABTS+ scavenging ability. Principal component analysis showed that total phenolic and flavonoid contents correlated well with observed antioxidants and anti-glycation activities. These results bring attention to the possible use of S. elaeagnifolium Cav as a valuable source of bioactive compounds exhibiting antioxidant effects and potentially alleviating diabetic complications.

Downloads

Published

2014-09-05

How to Cite

Houda, M., Derbré, S., Jedy, A., Tlili, N., Legault, J., Richomme, P., … Saidani-Tounsi, M. (2014). Combined anti-ages and antioxidant activities of different solvent extracts of Solanum elaeagnifolium Cav (Solanacea) fruits during ripening and related to their phytochemical compositions. EXCLI Journal, 13, 1029–1042. Retrieved from https://www.excli.de/index.php/excli/article/view/758

Issue

Vol. 13 (2014)

Section

Original articles

License

Authors who publish in this journal agree to the following terms:

  • The authors keep the copyright and grant the journal the right of first publication under the terms of the Creative Commons Attribution license, CC BY 4.0. This licencse permits unrestricted use, distribution and reproduction in any medium, provided that the original work is properly cited.
  • The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.
  • Because the advice and information in this journal are believed to be true and accurate at the time of publication, neither the authors, the editors, nor the publisher accept any legal responsibility for any errors or omissions presented in the publication. The publisher makes no guarantee, express or implied, with respect to the material contained herein.
  • The authors can enter into additional contracts for the non-exclusive distribution of the journal's published version by citing the initial publication in this journal (e.g. publishing in an institutional repository or in a book).

Most read articles by the same author(s)