@article{Abdellatif_Boudjella_Zitouni_Hassani_2014, title={Chemical composition and antimicrobial activity of the essential oil from leaves of Algerian Melissa officinalis L.}, volume={13}, url={https://www.excli.de/index.php/excli/article/view/739}, abstractNote={<p>The essential oil obtained from leaves of <i>Melissa officinalis</i> L. (Family of Lamiaceae) growing in Algeria, was investigated for its chemical composition and <i>in vitro</i> antimicrobial activity. The chemical composition was determined by hydrodistillation and analyzed by GC/MS and GC-FID. Sixty-three compounds were identified in the essential oil, representing 94.10 % of the total oil and the yields were 0.34 %. The major component was geranial (44.20 %). Other predominant components were neral (30.20 %) and citronellal (6.30 %). The <i>in vitro</i> antimicrobial activity was determined by paper disk agar diffusion testing and minimum inhibitory concentration (MIC) using 7 bacteria (3 Gram-positive and 4 Gram-negative), 2 yeasts and 3 fungi. The results showed that the essential oil presented high antimicrobial activity against all microorganisms targeted mainly against five human pathogenic bacteria, one yeast <i>Candida albicans</i> and two phytopathogenic fungi tested. The minimum inhibitory concentrations (MIC) ranged from 1.00 to 5.00 µL/mL.</p>}, journal={EXCLI Journal}, author={Abdellatif, Fahima and Boudjella, Hadjira and Zitouni, Abdelghani and Hassani, Aicha}, year={2014}, month={Jul.}, pages={772–781} }