Letter to the editor
Current biological and pharmacological updates on Tinospora cordifolia
Shubham Kumar1, Murtaza M. Tambuwala2, Yachana Mishra3, Vijay Mishra1
1School of Pharmaceutical Sciences, Lovely Professional University, Phagwara (Punjab)-144411, India
2College of Pharmacy, Ras Al Khaimah Medical and Health Sciences University, Ras Al Khaimah, United Arab Emirates
3School of Bioengineering and Biosciences, Lovely Professional University, Phagwara (Punjab)-144411, India
EXCLI J 2024;23:Doc811
Guduchi, scientifically known as Tinospora cordifolia, is one of the non-controversial and extensively used herbs in Ayurvedic medicine belonging to the family Menispermaceae (Sharma, 2017[17]). In the Ayurvedic healthcare system, guduchi is considered precious for its curative properties. The plant's numerous chemical contents, which are dispersed throughout its various plant sections, and each has unique medicinal properties, are responsible for its pharmacological actions. Glycosides, diterpenoid lactones, sesquiterpenoids, steroids, phenolic and aliphatic substances, essential oils, multiple kinds of fatty acids, polysaccharides, and tinosporaside (Figure 1(Fig. 1)) are among these chemical components (Ninama et al., 2022[9]). Only a few systematic reviews have been published highlighting the possible advantages of the plant, however, the majority of preclinical and clinical evidence demonstrated the wound healing, diabetes, hepatic, anti-toxic, anti-stress, inflammatory, and additional bioactive properties of T. cordifolia. As there is a scarcity of studies reflecting the therapeutic role of T. cordifolia, the present letter highlights the beneficial effects of T. cordifolia in the treatment of different diseases. Additionally, it gives researchers a direction for future research and suggests ways to improve the safety and effectiveness of T. cordifolia in treating a variety of diseases and other uses (Table 1(Tab. 1); References in Table 1: Ambalavanan et al., 2021[1]; Balkrishna et al., 2023[2]; Bhandari et al., 2022[3]; Gupta et al., 2018[4]; Kamboj et al., 2023[5]; Kumar et al., 2022[6]; Maya et al., 2022[7]; Mishra et al., 2023[8]; Philip et al., 2018[10]; Prakash Kumar et al., 2011[11]; Prasad and Chauhan, 2019[12]; Pushp et. al., 2013[13]; Salve et al., 2015[14]; Sarkar et al., 2023[15]; Sharma et al., 2019[16]; Singh et al., 2020[18]; Tiwari et al., 2014[19]; Yow et al., 2023[20]).
Declaration
None.
The authors declare no conflict of interest.
References
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Yow H-Y, Fernandez M, Kumar HSN, Azlina AA, Najwa M, Krishnappa P. The diabetic wound healing abilities of the aqueous ethanolic extract of tinospora cordifolia stem in streptozotocin - nicotinamide induced diabetic rats. Preprint Authorea. 2023. doi: 10.22541/au.169211012.24540041/v1
Figure 1: (A) Plant part of T. Cordifolia and (B) Chemical structure of Tinosporaside
Table 1: An update on the biological and pharmacological activities of Tinospora cordifolia