ctDNA as a novel and promising approach for cancer diagnosis
a focus on hepatocellular carcinoma
Keywords:ctDNA, hepatocellular carcinoma, cancer diagnosis, screening biomarkers, ctDNA detection
Hepatocellular carcinoma (HCC) is one of the most prevalent forms of cancer worldwide. Therefore, it is essential to diagnose and treat HCC patients promptly. As a novel discovery, circulating tumor DNA (ctDNA) can be used to analyze the tumor type and the cancer location. Additionally, ctDNA assists the cancer stage determination, which enables medical professionals to provide patients with the most appropriate treatment. This review will discuss the HCC-related mutated genes diagnosed by ctDNA. In addition, we will introduce the different and the most appropriate ctDNA diagnosis approaches based on the facilities.
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Copyright (c) 2023 Negin Biglari, Mohammad Sadegh Soltani-Zangbar, Jamal Mohammadian, Amir Mehdizadeh, Khadijeh Abbasi
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