Published continuously

Published: 2020-01-02

Original articles

The effects of synbiotic supplementation on serum inflammatory markers and edema volume in breast cancer survivors with lymphedema

Authors: Saeideh Vafa, Shahpar Haghighat, Leila Janani, Ali Saneei Totmaj, Mehraban Navaei, Ali Amirinejad, Hadi Emamat, Zahra Salehi, Mitra Zarrati
Pages: 1-15
Published: 2020-01-02
Issue: Vol. 19 (2020)
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5,6,7,4’-Tetramethoxyflavanone protects against neuronal degeneration induced by dexamethasone by attenuating amyloidogenesis in mice

Authors: Kanet Pakdeepak, Ratchanaporn Chokchaisiri, Jiraporn Tocharus, Pranglada Jearjaroen, Chainarong Tocharus, Apichart Suksamrarn
Pages: 16-32
Published: 2020-01-02
Issue: Vol. 19 (2020)
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Effect of Ficus glomerata leaf extract in streptozotocin-induced early diabetic complications and its characterization by LC-MS

Authors: Abusufyan Sirajuddin Shaikh, Mohammad Ibrahim, Mohib Khan, Dr.
Pages: 33-47
Published: 2020-01-03
Issue: Vol. 19 (2020)
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Redox status, DNA and HSA binding study of naturally occurring naphthoquinone derivatives

Authors: Milena D. Vukic, Nenad L. Vukovic, Ana Obradovic, Milos Matic, Maja Djukic, Edina Avdovic
Pages: 48-70
Published: 2020-01-03
Issue: Vol. 19 (2020)
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Phosphoinositide 3-kinase inhibitor AS605240 ameliorates streptozotocin-induced Alzheimer’s disease like sporadic dementia in experimental rats

Authors: Ramesh Alluri, Siva Mallikarjuna Reddy Ambati, Kasiviswanath Routhu, Spandana Rajendra Kopalli, Sushruta Koppula
Pages: 71-85
Published: 2020-01-06
Issue: Vol. 19 (2020)
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RNA-protein correlation of liver toxicity markers in HepaRG cells

Authors: Albert Braeuning, Almut Mentz, Felix F. Schmidt, Stefan P. Albaum, Hannes Planatscher, Jörn Kalinowski, Thomas O. Joos, Oliver Poetz, Dajana Lichtenstein
Pages: 135-153
Published: 2020-01-17
Issue: Vol. 19 (2020)
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Common transcriptional programs and the role of chemokine (C-C motif) ligand 20 (CCL20) in cell migration of cholangiocarcinoma

Authors: Hay Mar Win Maung, Waraporn Chan-On, Nawapol Kunkeaw, Prasong Khaenam
Pages: 154-166
Published: 2020-01-20
Issue: Vol. 19 (2020)
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CRISPR/Cas9-mediated knockout of MLL5 enhances apoptotic effect of cisplatin in HeLa cells in vitro

Authors: Mohammad Pirouzfar, Farshid Amiri, Mehdi Dianatpour, Mohammad Ali Takhshid
Pages: 170-182
Published: 2020-01-23
Issue: Vol. 19 (2020)
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The safety evaluation of FM101, an A3 adenosine receptor modulator, in rat, for developing as therapeutics of glaucoma and hepatitis

Authors: Chong-Woo Park, Chung-Tack Han, Yasue Sakaguchi, Jiyoun Lee, Hwa-Young Youn
Pages: 187-200
Published: 2020-02-12
Issue: Vol. 19 (2020)
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Association of biofilm formation with multi drug resistance in clinical isolates of Pseudomonas aeruginosa

Authors: Nazia Abdulhaq, Zeeshan Nawaz, Muhammad Asif Zahoor, Abu Baker Siddique
Pages: 201-208
Published: 2020-02-18
Issue: Vol. 19 (2020)
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Rational design of novel coumarins: A potential trend for antioxidants in cosmetics

Authors: Apilak Worachartcheewan, Veda Prachayasittkul, Supaluk Prachayasittkul, Visanu Tantivit, Chareef Yeeyahya, Virapong Prachayasittkikul
Pages: 209-226
Published: 2020-02-26
Issue: Vol. 19 (2020)
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Short term effects of coffee components consumption on gut microbiota in patients with non-alcoholic fatty liver and diabetes: A pilot randomized placebo-controlled, clinical trial

Authors: Asieh Mansour, Mohammad Reza Mohajeri-Tehrani, Sara Karimi, Milad Sanginabadi, Hossein Poustchi, Samaneh Enayati, Saeedeh Asgarbeik, Javad Nasrollahzadeh, Azita Hekmatdoost
Pages: 241-250
Published: 2020-03-02
Issue: Vol. 19 (2020)
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Effect of grape polyphenols on selected inflammatory mediators: A systematic review and meta-analysis randomized clinical trials

Authors: Fahimeh Haghighatdoost, Ali Gholami, Mitra Hariri
Pages: 251-267
Published: 2020-03-02
Issue: Vol. 19 (2020)
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Tumor-derived urinary exosomal long non-coding RNAs as diagnostic biomarkers for bladder cancer

Authors: Maryam Abbastabar, Mohammad Sarfi, Abolfazl Golestani, Ali Karimi, Gholamreza Pourmand, Ehsan Khalili
Pages: 301-310
Published: 2020-03-04
Issue: Vol. 19 (2020)
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Possible involvement of the opioidergic system in the modulation of body temperature, jumping behavior and memory process in cholestatic and addicted mice

Authors: Mohammad-Reza Zarrindast, Yasaman Issazadeh, Niloofar Rezaei, Fatemeh Khakpai
Pages: 311-322
Published: 2020-03-04
Issue: Vol. 19 (2020)
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Antitrypanosomal butanolides from Aiouea trinervis

Authors: Felipe Oliveira Nunes, Júlio Menta de Almeida, Alda Maria Teixeira Ferreira, Letícia Alves da Cruz, Camila Mareti Bonin Jacob, Walmir Silva Garcez, Fernanda Rodrigues Garcez
Pages: 323-333
Published: 2020-03-06
Issue: Vol. 19 (2020)
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The small chain fatty acid butyrate antagonizes the TCR-stimulation-induced metabolic shift in murine epidermal γδ T cells

Authors: Lukas Häselbarth, D. Margriet Ouwens, Nadine Teichweyde, Katrin Hochrath, Katja Merches, Charlotte Esser
Pages: 334-350
Published: 2020-03-09
Issue: Vol. 19 (2020)
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Involvement of haptoglobin phenotypes and genotypes in non-muscle invasive bladder cancer: A possible prognostic marker for risk stratification

Authors: Nazi Aghaalikhani, Mojtaba Zamani, Abdolamir Allameh, Amir Mashayekhi, Pejman Shadpour, Marzieh Mahmoodi, Nadereh Rashtchizadeh
Pages: 351-359
Published: 2020-03-10
Issue: Vol. 19 (2020)
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Broad-spectrum antimicrobial activity of wetland-derived Streptomyces sp. ActiF450

Authors: Mabrouka Benhadj, Roumaisa Metrouh, Taha Menasria, Djamila Gacemi-Kirane, Fatma Zohra Slim, Stephane Ranque
Pages: 360-371
Published: 2020-03-12
Issue: Vol. 19 (2020)
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The effects of occupational exposure to manganese fume on neurobehavioral and neurocognitive functions: An analytical cross-sectional study among welders

Authors: Younes Mehrifar, Mahshid Bahrami, Esmail Sidabadi, Hamideh Pirami
Pages: 372-386
Published: 2020-03-13
Issue: Vol. 19 (2020)
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Role of Kupffer cells in liver injury induced by CpG oligodeoxynucleotide and flucloxacillin in mice

Authors: Yuying Gao, Binbin Song, Shigeki Aoki, Kousei Ito
Pages: 387-399
Published: 2020-03-13
Issue: Vol. 19 (2020)
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Unrevealing sequence and structural features of novel coronavirus using in silico approaches: The main protease as molecular target

Authors: Joseph Thomas Ortega, Maria Luisa Serrano, Flor Helene Pujol, Hector Rafael Rangel
Pages: 400-409
Published: 2020-03-17
Issue: Vol. 19 (2020)
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Role of changes in SARS-CoV-2 spike protein in the interaction with the human ACE2 receptor: An in silico analysis

Authors: Joseph Thomas Ortega, Maria Luisa Serrano, Flor Helene Pujol, Hector Rafael Rangel
Pages: 410-417
Published: 2020-03-18
Issue: Vol. 19 (2020)
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Toxic responses of the liver and kidneys following occupational exposure to anesthetic gases

Authors: Masoud Neghab, Fatemeh Amiri, Esmaeel Soleimani, Saeed Yousefinejad, Jafar Hassanzadeh
Pages: 418-429
Published: 2020-03-25
Issue: Vol. 19 (2020)
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Analysis of Natural Killer cell functions in patients with hereditary hemochromatosis

Authors: Vivian Bönnemann, Maren Claus, Barbara Butzeck, Daniela Collette, Peter Bröde, Klaus Golka, Carsten Watzl
Pages: 430-441
Published: 2020-03-25
Issue: Vol. 19 (2020)
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Hygrophorus eburneus, edible mushroom, a promising natural bioactive agent

Authors: Marijana M. Kosanić, Dragana S. Šeklić, Milena M. Jovanović, Nevena Petrović, Snežana D. Marković
Pages: 442-457
Published: 2020-03-31
Issue: Vol. 19 (2020)
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QSAR-driven rational design of novel DNA methyltransferase 1 inhibitors

Authors: Chuleeporn Phanus-umporn, Veda Prachayasittikul, Chanin Nantasenamat, Supaluk Prachayasittikul, Virapong Prachayasittikul
Pages: 458-475
Published: 2020-04-02
Issue: Vol. 19 (2020)
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Association between HIC1 promoter methylation and solid tumor: A meta-analysis

Authors: Zhao Tie, Justice Afrifa, Dong Wang, Jingcui Yu
Pages: 476-489
Published: 2020-04-07
Issue: Vol. 19 (2020)
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Silver nanoparticles restrict microbial growth by promoting oxidative stress and DNA damage

Authors: Oluyomi Stephen Adeyemi, Emmanuella Oluwatosin Shittu, Oghenerobor Benjamin Akpor, Damilare E. Rotimi, Gaber El-saber Batiha
Pages: 492-500
Published: 2020-04-15
Issue: Vol. 19 (2020)
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Urinary PCA3 detection in prostate cancer by magnetic nanoparticles coupled with colorimetric enzyme-linked oligonucleotide assay

Authors: Vichanan Yamkamon, Khin Phyu Pyar Htoo, Sakda Yainoy, Thummaruk Suksrichavalit, Tienrat Tangchaikeeree, Warawan Eiamphungporn
Pages: 501-513
Published: 2020-04-15
Issue: Vol. 19 (2020)
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Toxoplasma gondii: Preventive and therapeutic effects of morphine and evaluation of treatment parameters of tachyzoites and infected macrophages in vitro and in a murine model

Authors: Leila Zaki, Fatemeh Ghaffarifar, Zohreh Sharifi, John Horton, Javid Sadraei
Pages: 514-527
Published: 2020-04-20
Issue: Vol. 19 (2020)
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Perifosine and vitamin D combination induces apoptotic and non-apoptotic cell death in endometrial cancer cells

Authors: Meryem Ilkay Karagul, Savas Aktas, Sakir Necat Yilmaz, Derya Yetkin, Havva Didem Celikcan, Ozge Selin Cevik
Pages: 532-546
Published: 2020-05-04
Issue: Vol. 19 (2020)
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The neural basis of hazard perception differences between novice and experienced drivers - An fMRI study

Authors: Seifollah Gharib, Arash Zare-Sadeghi, Seyed Abolfazl Zakerian, Mohsen Reza Haidari
Pages: 547-566
Published: 2020-05-04
Issue: Vol. 19 (2020)
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Fibroblast Growth Factor–21 ameliorates hepatic encephalopathy by activating the STAT3-SOCS3 pathway to inhibit activated hepatic stellate cells

Authors: Yeboah Kwaku Opoku, Zhihang Liu, Justice Afrifa, Asare Kwame Kumi, Han Liu, George Ghartey-Kwansah, Harriet Koranteng, Xinghao Jiang, Guiping Ren, Deshan Li
Pages: 567-581
Published: 2020-05-04
Issue: Vol. 19 (2020)
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Bioinformatics and experimental studies of anti-leukemic activity from 6-gingerol demonstrate its role in p53 mediated apoptosis pathway

Authors: Chawalit Chatupheeraphat, Chanin Nantasenamat, Kamolchanok Deesrisak, Sittiruk Roytrakul, Usanarat Anurathapan, Dalina Tanyong
Pages: 582-595
Published: 2020-05-06
Issue: Vol. 19 (2020)
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Synergistic effects of quercetin and regular exercise on the recovery of spatial memory and reduction of parameters of oxidative stress in animal model of Alzheimer's disease

Authors: Amin Molaei, Homeira Hatami, Gholamreza Dehghan, Reihaneh Sadeghian, Nazli Khajehnasiri
Pages: 596-612
Published: 2020-05-08
Issue: Vol. 19 (2020)
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Inhibition of prostate cancer cell line (PC-3) by anhydrodihydroartemisinin (ADHA) through caspase-dependent pathway

Authors: Faiz Ahmad, Amit Sarder, Rajesh Gour, Shibendra Kumar Lal Karna, Priya Arora, P. Ravindranathan Kartha, Yuba Raj Pokharel
Pages: 613-619
Published: 2020-05-11
Issue: Vol. 19 (2020)
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Aloin promotes cell apoptosis by targeting HMGB1-TLR4-ERK axis in human melanoma cells

Authors: Pan Li, Kai Ren, Yin yin Liang, Ji kai Liu, Zhuo wen Liang, Yong feng Zhang
Pages: 641-651
Published: 2020-05-14
Issue: Vol. 19 (2020)
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Effects of vitamin D3 supplementation on clinical symptoms, quality of life, serum serotonin (5-hydroxytryptamine), 5-hydroxy-indole acetic acid, and ratio of 5-HIAA/5-HT in patients with diarrhea-predominant irritable bowel syndrome: A randomized clinical trial

Authors: Masoumeh Khalighi Sikaroudi, Marjan Mokhtare, Farzad Shidfar, Leila Janani, AmirHossein Faghihi Kashani, Mohsen Masoodi, Shahram Agah, Afsaneh Dehnad, Shahrzad Shidfar
Pages: 652-667
Published: 2020-05-19
Issue: Vol. 19 (2020)
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The methanolic extract of Cinnamomum zeylanicum bark improves formaldehyde-induced neurotoxicity through reduction of phospho-tau (Thr231), inflammation, and apoptosis

Authors: Sara Sayad-Fathi, Arash Zaminy, Parvin Babaei, Fatemeh Yousefbeyk, Nasibeh Azizi, Ebrahim Nasiri
Pages: 671-686
Published: 2020-05-25
Issue: Vol. 19 (2020)
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Microbiological and virulence aspects of Rhodotorula mucilaginosa

Authors: Isabele Carrilho Jarros, Flávia Franco Veiga, Jakeline Luiz Corrêa, Isabella Letícia Esteves Barros, Marina Cristina Gadelha, Morgana F. Voidaleski, Neli Pieralisi, Raissa Bocchi Pedroso, Vânia A. Vicente, Melyssa Negri, Terezinha I Estivalet Svidzinski
Pages: 687-704
Published: 2020-05-27
Issue: Vol. 19 (2020)
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Molecular mechanism and health effects of 1,2-Naphtoquinone

Authors: Antonio Garcia Soares, Marcelo N. Muscara, Soraia K. P. Costa
Pages: 707-717
Published: 2020-06-03
Issue: Vol. 19 (2020)
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Proteomics profiling asthma induced-lysine acetylation

Authors: Xin-ming Su, Yuan Ren, Meng-lu Li, Shi-yao Bai, Na Yu, Ling-fei Kong, Jian Kang
Pages: 734-744
Published: 2020-06-04
Issue: Vol. 19 (2020)
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Differential expression of Scinderin and Gelsolin in gastric cancer and comparison with clinical and morphological characteristics

Authors: Toktam Sadat Tavabe Ghavami, Shiva Irani, Reza Mirfakhrai, Reza Shirkoohi
Pages: 750-761
Published: 2020-06-05
Issue: Vol. 19 (2020)
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Aerobic training and hydroalcoholic extracts of green tea improve pro-oxidant-antioxidant balance and histopathological score in the N-methyl-N-nitrosourea-induced prostate cancer model of rat

Authors: Zakaria Vahabzadeh, Mohammadraman Molodi, Bahram Nikkho, Marziyeh Saghebjoo, Saber Saedmocheshi, Fatemeh Zamani, Yazdan Roshani, Sina Babanzadeh
Pages: 762-772
Published: 2020-06-08
Issue: Vol. 19 (2020)
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Tumor mutation burden associated with miRNA-gene interaction outcome mediates the survival of patients with liver hepatocellular carcinoma

Authors: Qing-Jiang Yu, Yi-Zhi Liang, Xiao-Ping Mei, Tai-Yong Fang
Pages: 861-871
Published: 2020-06-22
Issue: Vol. 19 (2020)
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Roles of kininogen-1, basement membrane specific heparan sulfate proteoglycan core protein, and roundabout homolog 4 as potential urinary protein biomarkers in diabetic nephropathy

Authors: Piyada Na Nakorn, Supitcha Pannengpetch, Patcharee Isarankura-Na-Ayudhya, Chadinee Thippakorn, Ratana Lawung, Nuankanya Sathirapongsasuti, Chagriya Kitiyakara, Piyamitr Sritara, Prin Vathesatogkit, Chartchalerm Isarankura-Na-Ayudhya
Pages: 872-891
Published: 2020-06-24
Issue: Vol. 19 (2020)
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Induction and repression effects on CYP and transporter protein abundance by azole mixture uptake in rat liver

Authors: Helen Hammer, Flavia Schmidt, Tanja Heise, Constanze Knebel, Alexander Dabrowski, Hannes Planatscher, Carsten Kneuer, Philip Marx-Stoelting, Oliver Pötz
Pages: 904-916
Published: 2020-06-26
Issue: Vol. 19 (2020)
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Significance of E-cadherin and Vimentin as epithelial-mesenchymal transition markers in colorectal carcinoma prognosis

Authors: Zohreh Niknami, Ahad Muhammadnejad, Alireza Ebrahimi, Zahra Harsani, Reza Shirkoohi
Pages: 917-926
Published: 2020-06-26
Issue: Vol. 19 (2020)
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The therapeutic potential of losartan in lung metastasis of colorectal cancer

Authors: Milad Hashemzehi, Niloufar Naghibzadeh, Fereshteh Asgharzadeh, Asma Mostafapour, Seyed Mahdi Hassanian, Gordon A. Ferns, William C. Cho, Amir Avan, Majid Khazaei
Pages: 927-935
Published: 2020-06-29
Issue: Vol. 19 (2020)
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Phenoxodiol sensitizes metastatic colorectal cancer cells to 5-fluorouracil- and oxaliplatin-induced apoptosis through intrinsic pathway

Authors: Esra Yaylaci, Hacer Ilke Onen, Atiye Seda Yar Saglam
Pages: 936-949
Published: 2020-06-30
Issue: Vol. 19 (2020)
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Microglia enhances proliferation of neural progenitor cells in an in vitro model of hypoxic-ischemic injury

Authors: Supanee Chounchay, Stephen C. Noctor, Nuanchan Chutabhakdikul
Pages: 950-961
Published: 2020-07-03
Issue: Vol. 19 (2020)
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Octyl gallate induces hepatic steatosis in HepG2 cells through the regulation of SREBP-1c and PPAR-γ gene expression

Authors: Kelly Goulart Lima, Vitor Giancarlo Schneider Levorse, Maria Claudia Rosa Garcia, Bruno de Souza Basso, Bruna Pasqualotto Costa, Géssica Luana Antunes, Carolina Luft, Gabriela Viegas Haute, Léder Leal Xavier, Márcio Vinícius Fagundes Donadio, Jarbas Rodrigues de Oliveira
Pages: 962-971
Published: 2020-07-06
Issue: Vol. 19 (2020)
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Effect of sodium butyrate on HDAC8 mRNA expression in colorectal cancer cell lines and molecular docking study of LHX1 - sodium butyrate interaction

Authors: Flora Forouzesh, Mahsa Ghiaghi, Hamzeh Rahimi
Pages: 1038-1051
Published: 2020-07-23
Issue: Vol. 19 (2020)
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Development of a novel in vitro assay to evaluate environmental water using an IL-8 reporter cell line

Authors: Yutaka Kimura, Chizu Fujimura, Toshifumi Imagawa, Socorro P. Lupisan, Mariko Saito-Obata, Mayuko Saito, Hitoshi Oshitani, Setsuya Aiba
Pages: 1054-1063
Published: 2020-07-31
Issue: Vol. 19 (2020)
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Exosomes derived from human mesenchymal stem cells preserve mouse islet survival and insulin secretion function

Authors: Somayeh Keshtkar, Maryam Kaviani, Fatemeh Sabet Sarvestani, Mohammad Hossein Ghahremani, Mahdokht Hossein Aghdaei, Ismail H. Al-Abdullah, Negar Azarpira
Pages: 1064-1080
Published: 2020-08-03
Issue: Vol. 19 (2020)
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Cytoprotective effects of fermented oyster extracts against oxidative stress-induced DNA damage and apoptosis through activation of the Nrf2/HO-1 signaling pathway in MC3T3-E1 osteoblasts

Authors: Cheol Park, Hyesook Lee, Min Ho Han, Jin-Woo Jeong, Sung Ok Kim, Soon-Jeong Jeong, Bae‐Jin Lee, Gi‐Young Kim, Eui Kyun Park, You‐Jin Jeon, Yung Hyun Choi
Pages: 1102-1119
Published: 2020-08-04
Issue: Vol. 19 (2020)
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LncRNA HOTAIR promotes MPP+-induced neuronal injury in Parkinson’s disease by regulating the miR-874-5p/ATG10 axis

Authors: Jingya Zhao, Hongli Li, Na Chang
Pages: 1141-1153
Published: 2020-08-05
Issue: Vol. 19 (2020)
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Association between resilience and a functional polymorphism in the serotonin transporter (SLC6A4) gene: A meta-analysis

Authors: Yeimy González-Giraldo, Diego A. Forero
Pages: 1174-1183
Published: 2020-08-19
Issue: Vol. 19 (2020)
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Plasma vascular endothelial growth factor B is elevated in non-alcoholic fatty liver disease patients and associated with blood pressure and renal dysfunction

Authors: Xiaofeng Ye, Wen Kong, Mohammad Ishraq Zafar, Junchao Zeng, Rui Yang, Lu-Lu Chen
Pages: 1186-1195
Published: 2020-08-20
Issue: Vol. 19 (2020)
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Curcumin as an indirect methylation inhibitor modulates the effects of Toxoplasma gondii on genes involved in male fertility

Authors: Jasem Saki, Mohamad Sabaghan, Reza Arjmand, Ali Teimoori, Mohammad Rashno, Ghasem Saki, Saeedeh Shojaee
Pages: 1196-1207
Published: 2020-08-24
Issue: Vol. 19 (2020)
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Knockdown of CSNK2β suppresses MDA-MB231 cell growth, induces apoptosis, inhibits migration and invasion

Authors: Shibendra Kumar Lal Karna, Bilal Ahmad Lone, Faiz Ahmad, Nerina Shahi, Yuba Raj Pokharel
Pages: 1211-1226
Published: 2020-09-07
Issue: Vol. 19 (2020)
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Polygonum minus essential oil modulates cisplatin-induced hepatotoxicity through inflammatory and apoptotic pathways

Authors: Norhashima Abd Rashid, Farida Hussan, Asmah Hamid, Nurul Raudzah Adib Ridzuan, Syarifah Aisyah Syed Abdul Halim, Nahdia Afiifah Abdul Jalil, Nor Haliza Mohamad Najib, Seong Lin Teoh, Siti Balkis Budin
Pages: 1246-1265
Published: 2020-09-09
Issue: Vol. 19 (2020)
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Assessment of trimethylamine-N-oxide at the blood-cerebrospinal fluid barrier: Results from 290 lumbar punctures

Authors: Dietmar Enko, Sieglinde Zelzer, Tobias Niedrist, Sandra Holasek, Andreas Baranyi, Wolfgang J. Schnedl, Markus Herrmann, Andreas Meinitzer
Pages: 1275-1281
Published: 2020-09-09
Issue: Vol. 19 (2020)
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Prosopis juliflora leave extracts induce cell death of MCF-7, HepG2, and LS-174T cancer cell lines

Authors: Serag Eldin I. Elbehairi, Ahmed Ezzat Ahmed, Ali A. Alshati, Mohammed A. Al-Kahtani, Mohammad Y. Alfaifi, Khalid M. Alsyaad, Ali Yahya A. Alalmie, Mohammed M. Elimam Ahamed, Mahmoud F. Moustafa, Sadeq K. Alhag, Ahmed M. Al-Abd, Ahmed M. Abbas
Pages: 1282-1294
Published: 2020-09-09
Issue: Vol. 19 (2020)
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Negative impact of COVID-19 pandemic on sleep quantitative parameters, quality, and circadian alignment

Implications for health and psychological well-being

Authors: Mohammad Ali Salehinejad, Maryam Majidinezhad, Elham Ghanavati, Sahar Kouestanian, Carmelo M. Vicario, Michael A. Nitsche, Vahid Nejati
Pages: 1297-1308
Published: 2020-09-11
Issue: Vol. 19 (2020)
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The association of a genetic variant in CDKN2A/B gene and the risk of colorectal cancer

Authors: Farzad Rahmani, Amir Avan, Forouzan Amerizadeh, Gordon A. Ferns, Sahar Talebian, Soodabeh Shahidsales
Pages: 1316-1321
Published: 2020-09-14
Issue: Vol. 19 (2020)
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In vitro anticancer activity of Scrophularia amplexicaulis extracts on MCF-7 and WEHI-164 cell line

Authors: Samira Valiyari, Elham Beiranvand, Azin Samimi, Saeid Yaripour, Behzad Baradaran, Abbas Delazar, Mehdi Forouzesh
Pages: 1341-1352
Published: 2020-09-22
Issue: Vol. 19 (2020)
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Differential engulfment of Staphylococcus aureus and Pseudomonas aeruginosa by monocyte-derived macrophages is associated with altered phagocyte biochemistry and morphology

Authors: Mohamed El Mohtadi, Lisa Pilkington, Christopher M. Liauw, Jason J. Ashworth, Nina Dempsey-Hibbert, Amina Belboul, Kathryn A. Whitehead
Pages: 1372-1384
Published: 2020-09-30
Issue: Vol. 19 (2020)
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Downregulation of Sirt1 is correlated to upregulation of p53 and increased apoptosis in epicardial adipose tissue of patients with coronary artery disease

Authors: Mahdieh Khanahmadi, Babak Manafi, Heidar Tayebinia, Jamshid Karimi, Iraj Khodadadi
Pages: 1387-1398
Published: 2020-10-02
Issue: Vol. 19 (2020)
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Interleukin-6 is associated with tryptophan metabolism and signs of depression in individuals with carbohydrate malabsorption

Authors: Dietmar Enko, Sieglinde Zelzer, Julian Wenninger, Sandra Holasek, Wolfgang J. Schnedl, Andreas Baranyi, Markus Herrmann, Andreas Meinitzer
Pages: 1414-1422
Published: 2020-10-28
Issue: Vol. 19 (2020)
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Overexpression and translocation of dynamin 2 promotes tumor aggressiveness in breast carcinomas

Authors: Roya Sajed, Leili Saeednejad Zanjani, Mandana Rahimi, Maryam Mansoori, Amir-Hassan Zarnani, Zahra Madjd, Roya Ghods
Pages: 1423-1435
Published: 2020-10-29
Issue: Vol. 19 (2020)
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Revealing the astragalin mode of anticandidal action

Authors: Marija Ivanov, Abhilash Kannan, Dejan Stojkovic, Jasmina Glamočlija, Simona Golič Grdadolnik, Dominique Sanglard, Marina Soković
Pages: 1436-1445
Published: 2020-10-29
Issue: Vol. 19 (2020)
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Overexpression of miRNA-145 induces apoptosis and prevents proliferation and migration of MKN-45 gastric cancer cells

Authors: Tahereh Zeinali, Leila Karimi, Nayer Hosseinahli, Dariush Shanehbandi, Behzad Mansoori, Ali Mohammadi, Khalil Hajiasgharzadeh, Zohreh Babaloo, Jafar Majidi-Zolbanin, Behzad Baradaran
Pages: 1446-1458
Published: 2020-11-03
Issue: Vol. 19 (2020)
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Genome-wide expression changes induced by bisphenol A, F and S in human stem cell derived hepatocyte-like cells

Authors: B. Lucendo-Villarin, Patrick Nell, Birte Hellwig, P. Filis, David Feuerborn, P. J. O'Shaughnessy, Patricio Godoy, Jörg Rahnenführer, Jan G. Hengstler, A. Cherianidou, A. Sachinidis, P. A. Fowler, David C. Hay
Pages: 1459-1476
Published: 2020-11-04
Issue: Vol. 19 (2020)
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Bio-impedance measurement allows displaying the early stages of neutrophil extracellular traps

Authors: Caren Linnemann, Sascha Venturelli, Franziska Konrad, Andreas K. Nussler, Sabrina Ehnert
Pages: 1481-1495
Published: 2020-11-05
Issue: Vol. 19 (2020)
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iTRAQ-based proteomics reveals serum protein changes in hypertensive rats induced by a high-salt diet

Authors: Ying Qin, Tao Dong, Wan Jiang, Wen Ding, Tao Zhan, Juan Du, Ren Zhao, Bing Shen, Jiexia Chen
Pages: 1496-1511
Published: 2020-11-06
Issue: Vol. 19 (2020)
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Circ_0010729 knockdown protects cardiomyocytes against hypoxic dysfunction via miR-370-3p/TRAF6 axis

Authors: Jingjing Zhang, Chuanyu Gao, Jing Zhang, Famin Ye
Pages: 1520-1532
Published: 2020-11-11
Issue: Vol. 19 (2020)
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Clinical characteristics and outcomes of diabetics hospitalized for COVID-19 infection: a single-centered, retrospective, observational study

Authors: Asieh Mansour, Sayed Mahmoud Sajjadi-Jazi, Amir Kasaeian, Bardia Khosravi, Majid Sorouri, Fatemeh Azizi, Zeinab Rajabi, Fatemeh Motamedi, Azin Sirusbakht, Masoud Eslahi , Heila Mojtabbavi, Ali Reza Sima, Amir Reza Radmard, Mohhamad Reza Mohajeri-Tehrani, Mohammad Abdollahi
Pages: 1533-1543
Published: 2020-11-16
Issue: Vol. 19 (2020)
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Review articles

Ovariectomized rat model of osteoporosis: a practical guide

Authors: Nasibeh Yousefzadeh, Khosrow Kashfi, Sajad Jeddi, Asghar Ghasemi
Pages: 89-107
Published: 2020-01-10
Issue: Vol. 19 (2020)
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The survival rate of hepatocellular carcinoma in Asian countries: a systematic review and meta-analysis

Authors: Soheil Hassanipour, Mouhebat Vali, Saber Gaffari-fam, Hossein-Ali Nikbakht, Elham Abdzadeh, Farahnaz Joukar, Akram Pourshams, Afshin Shafaghi, Mahdi Malakoutikhah, Morteza Arab-Zozani, Hamid Salehiniya, Fariborz Mansour-Ghanaei
Pages: 108-130
Published: 2020-01-13
Issue: Vol. 19 (2020)
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Serotonergic system modulation holds promise for L‐DOPA‐induced dyskinesias in hemiparkinsonian rats: A systematic review

Authors: Fereshteh Farajdokht, Saeed Sadigh-Eteghad, Alireza Majdi, Fariba Pashazadeh, Seyyed Mehdi Vatandoust, Mojtaba Ziaee, Fatemeh Safari, Pouran Karimi, Javad Mahmoudi
Pages: 268-295
Published: 2020-03-02
Issue: Vol. 19 (2020)
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Artificial sweeteners are related to non-alcoholic fatty liver disease: Microbiota dysbiosis as a novel potential mechanism

Authors: Hadi Emamat, Hamid Ghalandari, Hadith Tangestani, Afsoun Abdollahi, Azita Hekmatdoost
Pages: 620-626
Published: 2020-05-12
Issue: Vol. 19 (2020)
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Prognostic role of immune cells in hepatocellular carcinoma

Authors: Meenakshi Sachdeva, Sunil K. Arora
Pages: 718-733
Published: 2020-06-03
Issue: Vol. 19 (2020)
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3Rs toxicity testing and disease modeling projects in the European Horizon 2020 research and innovation program

Authors: Mathieu Vinken
Pages: 775-784
Published: 2020-06-09
Issue: Vol. 19 (2020)
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Anaplastic thyroid cancer: How far can we go?

Authors: Mariana Amaral, Ricardo A. Afonso, Maria Manuela Gaspar, Catarina Pinto Reis
Pages: 800-812
Published: 2020-06-15
Issue: Vol. 19 (2020)
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Pathophysiology and therapy of systemic vasculitides

Authors: Massimo Ralli, Flaminia Campo, Diletta Angeletti, Antonio Minni, Marco Artico, Antonio Greco, Antonella Polimeni, Marco de Vincentiis
Pages: 817-854
Published: 2020-06-18
Issue: Vol. 19 (2020)
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Sulforaphane treatment for autism spectrum disorder: A systematic review

Authors: Greer McGuinness, Yeonsoo Kim
Pages: 892-903
Published: 2020-06-26
Issue: Vol. 19 (2020)
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Inorganic nitrate, a natural anti-obesity agent: A systematic review and meta-analysis of animal studies

Authors: Zahra Bahadoran, Sajad Jeddi, Sevda Gheibi, Parvin Mirmiran, Khosrow Kashfi, Asghar Ghasemi
Pages: 972-983
Published: 2020-07-06
Issue: Vol. 19 (2020)
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Current coronavirus (SARS-CoV-2) epidemiological, diagnostic and therapeutic approaches: An updated review until June 2020

Authors: Ahmed Nabil, Koichiro Uto, Mohamed M. Elshemy, Reham Soliman, Ayman A. Hassan, Mitsuhiro Ebara, Gamal Shiha
Pages: 992-1016
Published: 2020-07-20
Issue: Vol. 19 (2020)
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Osteoporosis: Pathophysiology and therapeutic options

Authors: Ursula Föger-Samwald, Peter Dovjak, Ursula Azizi-Semrad, Katharina Kerschan-Schindl, Peter Pietschmann
Pages: 1017-1037
Published: 2020-07-20
Issue: Vol. 19 (2020)
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State-dependent memory and its modulation by different brain areas and neurotransmitters

Authors: Mohammad-Reza Zarrindast, Fatemeh Khakpai
Pages: 1081-1099
Published: 2020-08-03
Issue: Vol. 19 (2020)
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Biomaterials based on noncovalent interactions of small molecules

Authors: Jiaqi Guo, Changhao Tian, Bing Xu
Pages: 1124-1140
Published: 2020-08-05
Issue: Vol. 19 (2020)
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Insulin secretion: The nitric oxide controversy

Authors: Sevda Gheibi, Asghar Ghasemi
Pages: 1227-1245
Published: 2020-09-08
Issue: Vol. 19 (2020)
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A review on biogenic synthesis, applications and toxicity aspects of zinc oxide nanoparticles

Authors: Rajat Sharma, Rajni Garg, Avnesh Kumari
Pages: 1325-1340
Published: 2020-09-22
Issue: Vol. 19 (2020)
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Interplay between reactive oxygen species and autophagy in the course of age-related macular degeneration

Authors: Małgorzata Nita, Andrzej Grzybowski
Pages: 1353-1371
Published: 2020-09-25
Issue: Vol. 19 (2020)
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Why we do what we do. A brief analysis of cancer therapies

Authors: Carlos Maria Galmarini
Pages: 1401-1413
Published: 2020-10-28
Issue: Vol. 19 (2020)
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Artificial Intelligence and its future potential in lung cancer screening

Authors: Christopher Joy Mathew, Ashwini Maria David, Chris Mariya Joy Mathew
Pages: 1552-1562
Published: 2020-12-11
Issue: Vol. 19 (2020)
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Immunology of IL-12: An update on functional activities and implications for disease

Authors: Karen Anne-Marie Ullrich, Lisa Lou Schulze, Eva-Maria Paap, Tanja Martina Müller, Markus F. Neurath, Sebastian Zundler
Pages: 1563-1589
Published: 2020-12-11
Issue: Vol. 19 (2020)
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Potential role of exosome in post-stroke reorganization and/or neurodegeneration

Authors: Fateme Azizi, Sahar Askari, Pegah Javadpour, Mahmoudreza Hadjighassem, Rasoul Ghasemi
Pages: 1590-1606
Published: 2020-12-11
Issue: Vol. 19 (2020)
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Editorial material

Highlight report: New insights in liver physiology: Canalicular bile flux is diffusion dominated

Authors: Ahmed Ezzat Ahmed
Pages: 1208-1210
Published: 2020-08-31
Issue: Vol. 19 (2020)
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Editor’s choice 2019: Oxidative stress and antineoplastic agents

Authors: Ahmed Ghallab
Pages: 1607-1609
Published: 2020-12-15
Issue: Vol. 19 (2020)
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Editor’s choice 2018: Non-coding RNAs in hepatocellular cancer

Authors: Ahmed Ghallab
Pages: 1615-1616
Published: 2020-12-22
Issue: Vol. 19 (2020)
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Case reports

Mental disorder or conscious disturbance in epidermal growth factor receptor-tyrosine kinase inhibitor treatment of advanced lung adenocarcinoma

Authors: Jing Zhu, Rui Zhou, Heng Xiao
Pages: 230-238
Published: 2020-02-28
Issue: Vol. 19 (2020)
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The effects of spaced transcranial Direct Current Stimulation combined with conventional dysphagia therapy in Parkinson’s disease: A case report

Authors: Ali Akbar Dashtelei, Michael A. Nitsche, Jalal Bakhtiyari, Seyed Amirhassan Habibi, Mojtaba Sepandi, Ahmad Reza Khatoonabadi
Pages: 745-749
Published: 2020-06-04
Issue: Vol. 19 (2020)
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Undifferentiated pleomorphic sarcoma in the anterior mediastinum with a rapidly progressive course: A case report

Authors: Masamichi Sato, Sumito Inoue, Tsuyoshi Arao, Akira Igarashi, Keiko Yamauchi, Kento Sato, Hiroshi Nakano, Masafumi Watanabe
Pages: 1161-1165
Published: 2020-08-17
Issue: Vol. 19 (2020)
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Severe rhabdomyolysis in homozygote carnitine palmitoyltransferase II deficiency

Authors: Wolfgang J. Schnedl, Michael Schenk, Dietmar Enko, Harald Mangge
Pages: 1309-1313
Published: 2020-09-11
Issue: Vol. 19 (2020)
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Letters to the editor

Concurrent chronic myeloid leukemia and CALR-mutated myeloproliferative neoplasm

Authors: Stephen E. Langabeer
Pages: 86-88
Published: 2020-01-08
Issue: Vol. 19 (2020)
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A recent overview on sulforaphane as a dietary epigenetic modulator

Authors: Tae Kyung Hyun
Pages: 131-134
Published: 2020-01-15
Issue: Vol. 19 (2020)
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Highlight Report: Hepatobiliary differentiation from human induced pluripotent stem cells

Authors: Patrick Nell
Pages: 167-169
Published: 2020-01-23
Issue: Vol. 19 (2020)
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Concomitant inflammation/metabolism transcriptional regulatory networks in liver disease

Authors: Tahany Abbas, Walaa Murad, Reham Hassan
Pages: 183-184
Published: 2020-01-27
Issue: Vol. 19 (2020)
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The in vivo genotoxicity of isotretinoin assessed by comet assay

Authors: Maede Bordbar, Zahra Zendeh-Boodi, Mostafa Saadat
Pages: 185-186
Published: 2020-02-10
Issue: Vol. 19 (2020)
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PPARG as therapeutic target for antifibrotic therapy

Authors: Ahmed Ghallab, Abdellatief Seddek
Pages: 227-229
Published: 2020-02-28
Issue: Vol. 19 (2020)
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In-utero exposure to opioid increases the risk of congenital heart defects

Authors: Kamleshun Ramphul, Stephanie G. Mejias, Jyotsnav Joynauth
Pages: 239-240
Published: 2020-03-02
Issue: Vol. 19 (2020)
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Linac-based radiotherapy for epicondylitis humeri

Authors: Mahmoud Navaser, Hamed Ghaffari, Mehrnaz Mashoufi, Soheila Refahi
Pages: 296-300
Published: 2020-03-04
Issue: Vol. 19 (2020)
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Activation of the ATX-LPA axis by carcinogenic chemicals: New leads to prevent pancreatic cancer?

Authors: Johan Högberg
Pages: 490-491
Published: 2020-04-09
Issue: Vol. 19 (2020)
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siRNA could be a potential therapy for COVID-19

Authors: Sanhita Ghosh, Sayeed Mohammad Firdous, Anirban Nath
Pages: 528-531
Published: 2020-04-22
Issue: Vol. 19 (2020)
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Recent studies on kaempferol and its biological and pharmacological activities

Authors: Jae Kwang Kim, Sang Un Park
Pages: 627-634
Published: 2020-05-13
Issue: Vol. 19 (2020)
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Current biological and pharmacological updates on wogonin

Authors: Sarita Rawat, Gaurav Gupta, Sachchidanand Pathak, Santosh Kumar Singh, Himmat Singh, Anurag Mishra, Ritu Gilhotra, Alaa A. A. Aljabali, Harish Dureja, Murtaza M. Tambuwala, Dinesh K. Chellappan, Kamal Dua
Pages: 635-640
Published: 2020-05-13
Issue: Vol. 19 (2020)
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Genotoxicity effect of methyl-tertiary butyl ether on rat lymphocytes using comet assay

Authors: Shima Alishahi, Zahra Zendeh-Boodi, Mostafa Saadat
Pages: 668-670
Published: 2020-05-25
Issue: Vol. 19 (2020)
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Nut consumption and risk of diabetes mellitus in overweight/obese individuals

Authors: Omid Eslami, Farzad Shidfar
Pages: 705-706
Published: 2020-05-29
Issue: Vol. 19 (2020)
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Can post-splenectomy thrombocytosis mask essential thrombocythaemia?

Authors: Stephen E. Langabeer
Pages: 773-774
Published: 2020-06-08
Issue: Vol. 19 (2020)
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COVID-19: Critical discussion on the applications and implications of chemicals in sanitizers and disinfectants

Authors: Olubunmi Atolani, Mariam Temitope Baker, Oluyomi Stephen Adeyemi, Ismaeel Ridwan Olanrewaju, Abdulmumeen A. Hamid, Oluduowo M. Ameen, Stephen O. Oguntoye, Lamidi A. Usman
Pages: 785-799
Published: 2020-06-15
Issue: Vol. 19 (2020)
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The multifactorial resistance of Pseudomonas aeruginosa

Authors: Amina Meliani
Pages: 813-816
Published: 2020-06-17
Issue: Vol. 19 (2020)
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Long time blood-transfusion trend in a European general hospital

Authors: Dietmar Enko, Markus Herrmann, Andreas Baranyi, Wolfgang J. Schnedl, Gabriele Halwachs-Baumann
Pages: 855-860
Published: 2020-06-19
Issue: Vol. 19 (2020)
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Recent insights into the biological functions of apigenin

Authors: Jae Kwang Kim, Sang Un Park
Pages: 984-991
Published: 2020-07-06
Issue: Vol. 19 (2020)
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Hepatotoxicity of anesthetic gases

Authors: Wiebke Albrecht
Pages: 1052-1053
Published: 2020-07-27
Issue: Vol. 19 (2020)
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The link between long-term nut consumption and health outcomes: A hard nut to crack?

Authors: Omid Eslami, Farzad Shidfar
Pages: 1100-1101
Published: 2020-08-03
Issue: Vol. 19 (2020)
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Recent pharmacological advances on genistein in clinical trials

Authors: Shimy Mathew, Cijo George Vazhappilly
Pages: 1120-1123
Published: 2020-08-05
Issue: Vol. 19 (2020)
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Anticancer activity of luteolin glycosides

Authors: Ahmed Ghallab
Pages: 1154-1155
Published: 2020-08-14
Issue: Vol. 19 (2020)
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Kupffer cells in hepatotoxicity

Authors: Reham Hassan
Pages: 1156-1157
Published: 2020-08-14
Issue: Vol. 19 (2020)
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Do artificial sweeteners increase the risk of non-alcoholic fatty liver disease (NAFLD)?

Authors: Tahany Abbas, Walaa Murad
Pages: 1158-1160
Published: 2020-08-14
Issue: Vol. 19 (2020)
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Vitamin D supplementation in COVID-19: A friend or foe?

Authors: Asieh Mansour, Mohammad Reza Mohajeri-Tehrani, Sayed Mahmoud Sajjadi-Jazi
Pages: 1166-1168
Published: 2020-08-17
Issue: Vol. 19 (2020)
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Rethinking “Exercise is Medicine”

Authors: Shunchang Li, Ismail Laher
Pages: 1169-1171
Published: 2020-08-18
Issue: Vol. 19 (2020)
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Which concentrations are optimal for in vitro testing?

Authors: Wiebke Albrecht
Pages: 1172-1173
Published: 2020-08-18
Issue: Vol. 19 (2020)
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Reproductive toxicity of boron

Authors: Florian Seidel
Pages: 1184-1185
Published: 2020-08-19
Issue: Vol. 19 (2020)
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Mitigation of metabolic dyshomeostasis by glucocorticoid-receptor antagonism: Insights from animal and human studies

Authors: Aishwariya Madhavan, Kusuma Murali, Vaishnavi Raghavendra, Apurva Kumar Ramesh Joshi
Pages: 1266-1274
Published: 2020-09-09
Issue: Vol. 19 (2020)
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Immune responses during neoadjuvant chemotherapy in triple negative breast cancer

Authors: Ahmed Ghallab
Pages: 1295-1296
Published: 2020-09-11
Issue: Vol. 19 (2020)
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Tea, coffee and risk of glioma

Authors: Tomoyuki Kawada
Pages: 1314-1315
Published: 2020-09-14
Issue: Vol. 19 (2020)
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Brazil’s research budget: endless setbacks

Authors: Lucindo José Quintans-Júnior, George Rego Albuquerque, Sérgio Campello Oliveira, Robério Rodrigues Silva
Pages: 1322-1324
Published: 2020-09-21
Issue: Vol. 19 (2020)
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Tea and coffee consumption, cognitive impairment and prognosis in older inhabitants

Authors: Tomoyuki Kawada
Pages: 1385-1386
Published: 2020-10-02
Issue: Vol. 19 (2020)
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CALR mutations in myeloproliferative neoplasms: An unfolding story

Authors: Stephen E. Langabeer
Pages: 1399-1400
Published: 2020-10-26
Issue: Vol. 19 (2020)
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Interferon therapy for preventing COPD exacerbations

Authors: Meenu Mehta, Keshav R. Paudel, Shakti D. Shukla, Madhur Shastri, Sachin K. Singh, Monica Gulati, Harish Dureja, Gaurav Gupta, Saurabh Satija, Philip M. Hansbro, Dinesh K. Chellappan, Kamal Dua
Pages: 1477-1480
Published: 2020-11-04
Issue: Vol. 19 (2020)
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Emerging prospects of vitamin D3 in metabolic syndrome: A proof of concept (POC) approach targeting inflammation

Authors: Yogendra Singh , Gaurav Gupta, Ritu M. Gilhotra, Sachin Kumar Singh, Parteek Prasher, Anand Krishnan , Kamal Dua, Dinesh Kumar Chellappan
Pages: 1512-1516
Published: 2020-11-09
Issue: Vol. 19 (2020)
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Ivermectin: Panacea or true promise for COVID-19

Authors: Luana Heimfarth, Victor Santana Santos, Adriano Antunes de Souza Araújo, Lucindo José Quintans-Júnior, Paulo Ricardo Martins-Filho
Pages: 1517-1519
Published: 2020-11-09
Issue: Vol. 19 (2020)
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What about incorporating selenium in the therapeutic regimen of SARS-CoV-2?

Authors: Bachir Benarba, Atanasio Pandiella
Pages: 1544-1546
Published: 2020-12-07
Issue: Vol. 19 (2020)
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Efficacy of tranexamic acid in patients with traumatic brain injury

Authors: Tomoyuki Kawada
Pages: 1547-1548
Published: 2020-12-08
Issue: Vol. 19 (2020)
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Microbial determinants of arthritis

Authors: Shakti D. Shukla, Madhur D. Shastri, Niraj Kumar Jha, Kamal Dua
Pages: 1549-1551
Published: 2020-12-09
Issue: Vol. 19 (2020)
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Examination of predictable factors of perioperative respiratory complications by preoperative forced oscillation technique parameters

Authors: Akira Igarashi, Sumito Inoue, Yoko Shibata, Keiko Nunomiya, Takahito Ota, Yu Ishibashi, Hiroaki Murano, Kodai Furuyama, Sujeong Yang, Hiroyoshi Machida, Hiroshi Nakano, Kento Sato, Masamichi Sato, Takako Nemoto, Michiko Nishiwaki, Keiko Yamauchi, Jun Suzuki, Mitsuaki Sadahiro, Masafumi Watanabe
Pages: 1610-1614
Published: 2020-12-21
Issue: Vol. 19 (2020)
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