Vol. 21 (2022)

Published continuously

Published: 2022-01-03

Original articles

Okadaic acid influences xenobiotic metabolism in HepaRG cells

Leonie T. D. Wuerger, Helen S. Hammer, Ute Hofmann, Felicia Kudiabor, Holger Sieg, Albert Braeuning

1053-1065
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Inorganic arsenic contamination and the health of children living near an inactive mining site: northern Thailand

Sarun Kunwittaya, Nootchanart Ruksee, Thirata Khamnong, Athiwat Jiawiwatkul, Nonthasruang Kleebpung, Vasunun Chumchua, Adisak Plitponkarnpim, Chutikorn Nopparat, Kannika Permpoonputtana

1007-1014
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Ameliorative effects of high intensity interval training and Lactobacillus rhamnosus GG against tetracycline-induced fatty liver in rats a gene expression profiling comparative study

Hamideh Mahmoodzadeh Hosseini, Hossein Shirvani, Fariba Aghaei, Ehsan Arabzadeh, Martin Hofmeister

991-1006
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Tryptophan recovery index as a new biomarker for fitness

Alexander Pichler, Andreas Meinitzer, Dietmar Enko, Peter Schober, Georg Singer, Christoph Castellani, Markus Herrmann, Sandra J. Holasek, Holger Till, Jana Maria Windhaber

888-896
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Transient receptor potential channel involvement in antinociceptive effect of citral in orofacial acute and chronic pain models

Sacha Aubrey Alves Rodrigues Santos, Marina de Barros Mamede Vidal Damasceno, Francisco Ernani Alves Magalhães, Barry John Sessle, Breytiner Amaro de Oliveira, Francisco Lucas Alves Batista, Antônio Eufrásio Vieira-Neto, Adriana Rolim Campos

869-887
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Integrated bioinformatics analysis reveals that EZH2-rich domains promote transcriptional repression in cervical cancer

Eric Genaro Salmerón-Bárcenas, Ana Elvira Zacapala-Gómez, Julio Ortiz-Ortiz, Francisco Israel Torres-Rojas, Pedro Antonio Avila-Lopez

852-868
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Immunomodulatory components of Trichinella spiralis excretory-secretory products with lactose-binding specificity

Natasa Ilic, Zanka Bojic-Trbojevic, Britta Lundström-Stadelmann, Danica Cujic, Ivana Mitic, Alisa Gruden-Movsesijan

793-813
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Plasma lncRNA profiling identified BC200 and NEAT1 lncRNAs as potential blood-based biomarkers for late-onset Alzheimer’s disease

Majid Khodayi, Mohammad Khalaj-Kondori, Mohammad Ali Hoseinpour Feizi, Mortaza Jabarpour Bonyadi, Mahnaz Talebi

772-785
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Ergonomic assessment of postal workers’ pain symptoms and musculoskeletal risks related to parcel processing activity for delivery

Lincoln Silva, Nélson Costa, Carolina Schutz Rosa, Irandir Izaquiel Paulo, Natália Mattos da Silva, Cesar Giracca, Sabrina da Silveira Simões, Adriana do Nascimento Aquini, Giselle Merino, Eugenio Andrés Díaz Merino

744-756
Cytotoxic capability and the associated proteomic profile of cell-free coelomic fluid extracts from the edible sea cucumber Holothuria tubulosa on HepG2 liver cancer cells

Claudio Luparello, Rossella Branni, Giulia Abruscato, Valentina Lazzara, Laszlo Drahos, Vincenzo Arizza, Manuela Mauro, Vita Di Stefano, Mirella Vazzana

722-743
Transplantation of SDF-1α-loaded liver extracellular matrix repopulated with autologous cells attenuated liver fibrosis in a rat model

Mostafa Najar-Asl, Hossein Bahadoran, Mohammad-Hossein Asadi, Mona Saheli, Mohammad-Hassan Asghari, Niloofar Sodeifi, Mohammad Kazemi Ashtiani, Massoud Vosough, Hossein Baharvand, Abbas Piryaei

704-721
Medical history, medication use and physical activity in adults in their eighth and ninth decade of life in the Hertfordshire Cohort Study

Gregorio Bevilacqua, Jean Zhang, Camille Parsons, Faidra Laskou, Nicholas Fuggle, Cyrus Cooper, Elaine Dennison

695-703
The “identikit” of subject with obesity and COVID-19 vaccine breakthrough

Giovanna Muscogiuri, Luigi Barrea, Ludovica Verde, Claudia Vetrani, Silvia Savastano, Annamaria Colao

687-694
The diaryl-imidazopyridazine anti-plasmodial compound, MMV652103, exhibits anti-breast cancer activity

Alexis Neumann-Mufweba, Serah Kimani, Saif Feroz Khan, Kelly Chibale, Sharon Prince

656-679
Analyzing the interaction of human ACE2 and RBD of spike protein of SARS-CoV-2 in perspective of Omicron variant

Arijit Samanta, Syed Sahajada Mahafujul Alam, Safdar Ali, Mehboob Hoque

610-620
Low-toxic herbicides Roundup and Atrazine disturb free radical processes in Daphnia in environmentally relevant concentrations

Viktor Husak, Tetiana Strutynska, Nadia Burdyliuk, Anzhelika Pitukh, Volodymyr Bubalo, Halyna Falsfushynska, Olha Strilbytska, Oleh Lushchak

595-609
Analysis of hematological parameters in rheumatoid arthritis patients receiving biological therapy contribution to prevention of avoidable hematological complications

Jana Pereckova, Silvia Martiniakova, Juraj Payer, Martin Falk, Zdenko Killinger, Tomas Perecko

580-594
Hypoxia-inducible factor (HIF)-3α2 serves as an endothelial cell fate executor during chronic hypoxia

Maciej Jaśkiewicz, Adrianna Moszyńska, Marcin Serocki, Jarosław Króliczewski, Sylwia Bartoszewska, James F. Collawn, Rafal Bartoszewski

454-469
IKBKE-driven TPL2 and MEK1 phosphorylations sustain constitutive ERK1/2 activation in tumor cells

Serkan Ismail Göktuna

436-453
Helicobacter pylori infection and lactose intolerance increase expiratory hydrogen

Wolfgang J. Schnedl, Nathalie Meier-Allard, Michael Schenk, Sonja Lackner, Dietmar Enko, Harald Mangge, Sandra J. Holasek

426-435
Molecular docking and mouse modeling suggest CMKLR1 and INSR as targets for improving PCOS phenotypes by minocycline

Mahdie Kian, Elham Hosseini, Tooba Abdizadeh, Taimour Langaee, Azadeh Khajouei, Sorayya Ghasemi

400-414
Phlomis fruticosa L. exerts in vitro antineurodegenerative and antioxidant activities and induces prooxidant effect in glioblastoma cell line

Dejan Stojković, Danijela Drakulić, Maria Inês Dias, Gokhan Zengin, Lillian Barros, Marija Ivanov, Uroš Gašić, Nemanja Rajčević, Milena Stevanović, Isabel C. F. R. Ferreira, Marina Soković

387-399
Synthesis of acetamidosulfonamide derivatives with antioxidative and QSAR studies

Apilak Worachartcheewan, Somchai Pisutjaroenpong, Ratchanok Pingaew, Supaluk Prachayasittikul, Suphakit Siriwong, Somsak Ruchirawat, Virapong Prachayasittikul

360-379
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How to keep up with the analysis of classic and emerging neurotoxins: Age-resolved fitness tests in the animal model Caenorhabditis elegans a step-by-step protocol

Indra Hering, Dang Tri Le, Anna von Mikecz

344-353
Ultrasound–guided posterior quadratus lumborum block for postoperative pain control after minimally invasive radical prostatectomy a randomized, double–blind, placebo–controlled trial

Bartosz Horosz, Katarzyna Białowolska, Anna Kociuba, Jakub Dobruch, Małgorzata Malec-Milewska

335-343
Pupil size as an indicator of cognitive activity in mild Alzheimer’s disease

Mohamad El Haj, Guillaume Chapelet, Ahmed A. Moustafa, Claire Boutoleau-Bretonnière

307-316
Inconsistent eating time is associated with obesity A prospective study

Darbaz Adnan, Jonathan Trinh, Faraz Bishehsari

300-306
Enhancing the efficacy of albendazole for liver cancer treatment using mesoporous silica nanoparticles an in vitro study

Mohsen Ghaferi, Warda Zahra, Azim Akbarzadeh, Hasan Ebrahimi Shahmabadi, Seyed Ebrahim Alavi

236-249
Preclinical safety profile of a liver-localized mitochondrial uncoupler OPC-163493

Yuki Inoue, Junichi Kino, Nobuya Ishiharada, Makoto Sato, Suguru Hatanaka, Hiroyuki Yokoi, Takahiro Shimada, Seiji Sato, Takashi Okamoto, Naohide Kanemoto

213-235
Cyclophosphamide and epirubicin induce high apoptosis in microglia cells while epirubicin provokes DNA damage and microglial activation at sub-lethal concentrations

Rafael de la Hoz-Camacho, Ana Luisa Rivera-Lazarin, Jose Manuel Vazquez-Guillen, Diana Caballero-Hernandez, Edgar Mendoza-Gamboa, Ana Carolina Martinez-Torres, Cristina Rodriguez-Padilla

197-212
Continous, non-invasive monitoring of oxygen consumption in a parallelized microfluidic in vitro system provides novel insight into the response to nutrients and drugs of primary human hepatocytes

Marius Busche, Dominik Rabl, Jan Fischer, Christian Schmees, Torsten Mayr, Rolf Gebhardt, Martin Stelzle

144-161
Hypermethylation of RAD9A intron 2 in childhood cancer patients, leukemia and tumor cell lines suggest a role for oncogenic transformation

Danuta Galetzka, Julia Böck, Lukas Wagner, Marcus Dittrich, Olesja Sinizyn , Marco Ludwig, Heidi Rossmann, Claudia Spix, Markus Radsak, Peter Scholz-Kreisel, Johanna Mirsch, Matthias Linke, Walburgis Brenner, Manuela Marron, Alicia Poplawski, Thomas Haaf, Heinz Schmidberger, Dirk Prawitt

117-143
Prevalence and predictors of adequate treatment of overt hypothyroidism – a population-based study

Julie Lindgård Nielsen, Jesper Karmisholt, Inge Bülow Pedersen, Allan Carlé

104-116
The COVID-19 vaccination acceptance/hesitancy rate and its determinants among healthcare workers of 91 Countries A multicenter cross-sectional study

Mehrdad Askarian, Aleksandr Semenov, Ferran Llopis, Francesca Rubulotta, Gorana Dragovac, Natalia Pshenichnaya, Ojan Assadian, Yvon Ruch, Zahra Shayan, Cristobal Padilla Fortunatti, Daniel Lucey, Abdullah Almohaizeie, Abu Hena Mostafa Kamal, Adenike Ogunshe, Aidos Konkayev, Asim Beg, Enzo Primerano, Fatma Amer, Hema Prakash Kumari Pilli, Ivan Hung, Folusakin Ayoade, Jean Yves Lefrant, Joanna Zajkowska, Jordi Rello, Momin Kazi, Mohammad Hossein Taghrir, Stijn Blot, Stephen Leib, Parisa Hosseinpour, Hamidreza Hosseinpour, Amirhossein Erfani, Roham Borazjani, Hossein Akbarialiabad, Masoud Najafi, Ardalan Askarian, Hakan Erdem

93-103
Feeding to satiation induces mild oxidative/carbonyl stress in the brain of young mice

Oksana V. Kuzniak, Oksana M. Sorochynska, Maria M. Bayliak, Andrii Ya. Klonovskyi, Yulia V. Vasylyk, Halyna M. Semchyshyn, Kenneth B. Storey, Olga Garaschuk, Volodymyr I. Lushchak

77-92
Risk factors, time to onset and recurrence of delirium in a mixed medical-surgical ICU population A secondary analysis using Cox and CHAID decision tree modeling

Farshid Rahimibashar, Andrew C. Miller, Mahmood Salesi, Motahareh Bagheri, Amir Vahedian-Azimi, Sara Ashtari, Keivan Gohari Moghadam, Amirhossein Sahebkar

30-46
Sex-specific differences in trimethylamine N-oxide (TMAO) concentrations before and after cardiac rehabilitation in acute myocardial infarction patients

Andreas Baranyi, Andreas Meinitzer, Dirk von Lewinski, Hans-Bernd Rothenhäusler, Omid Amouzadeh-Ghadikolai, Hanns Harpf, Leonhard Harpf, Heimo Traninger, Ronald Hödl, Birgit M. Harb, Barbara Obermayer-Pietsch, Melanie Schweinzer, Celine K. Braun, Dietmar Enko

1-10

Review articles

Nanocarriers for delivery of siRNA as gene silencing mediator

Aideé Morales-Becerril, Liliana Aranda-Lara, Keila Isaac-Olivé, Blanca E. Ocampo-García, Enrique Morales-Avila

1028-1052
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Pivotal role of vitamin D in mitochondrial health, cardiac function, and human reproduction

Alavala Matta Reddy, Mumtaz Iqbal, Hitesh Chopra, Shaheda Urmi, Sunil Junapudi, Shabana Bibi, Santosh Kumar Gupta, Viajaya Nirmala Pangi, Inderbir Singh, Mohamed M. Abdel-Daim

967-990
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Selenium as an important factor in various disease states a review

Marek Kieliszek, Iqra Bano

948-966
- Article - PDF
Insights into the mechanisms of non-coding RNAs’ implication in the pathogenesis of Alzheimer’s disease

Majid Khodayi-Shahrak, Mohammad Khalaj-Kondori, Mohammad Ali Hosseinpour Feizi, Mahnaz Talebi

921-940
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Elevated risk of thrombotic manifestations of SARS-CoV-2 infection in cancer patients A literature review

Annunziata Stefanile, Maria Cellerino, Tatiana Koudriavtseva

906-920
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Effects of curcumin on low-density lipoprotein oxidation From experimental studies to clinical practice

Fatemeh Baratzadeh, Alexandra E. Butler, Prashant Kesharwani, Seyed Adel Moallem, Amirhossein Sahebkar

840-851
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The association of ACE1, ACE2, TMPRSS2, IFITM3 and VDR polymorphisms with COVID-19 severity A systematic review and meta-analysis

Zorana Dobrijević, Dragana Robajac, Nikola Gligorijević, Miloš Šunderić, Ana Penezić, Goran Miljuš, Olgica Nedić

818-839
- Article - PDF
Recent development of machine learning-based methods for the prediction of defensin family and subfamily

Phasit Charoenkwan, Nalini Schaduangrat, S. M. Hasan Mahmud, Orawit Thinnukool, Watshara Shoombuatong

757-771
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Systems redox biology in health and disease

Martin Feelisch, Miriam M. Cortese-Krott, Jérôme Santolini, Stephen A. Wootton, Alan A. Jackson

623-646
Empirical comparison and analysis of machine learning-based predictors for predicting and analyzing of thermophilic proteins

Phasit Charoenkwan, Nalini Schaduangrat, Md Mehedi Hasan, Mohammad Ali Moni, Pietro Lió, Watshara Shoombuatong

554-570
The effect of exercise interventions on Irisin level a systematic review and meta-analysis of randomized controlled trials

Gholam Rasul Mohammad Rahimi, Keyvan Hejazi, Martin Hofmeister

524-539
- Article - PDF
Oxidative stress and visual system a review

Samanta Taurone, Massimo Ralli, Marco Artico, Valentina Noemi Madia, Susanna Scarpa, Stefania Annarita Nottola, Antonio Maconi, Marta Betti, Pietro Familiari, Marcella Nebbioso, Roberta Costi, Alessandra Micera

544-553
Quantitative aspects of nitric oxide production from nitrate and nitrite

Asghar Ghasemi

470-486
Evaluating the adverse outcome of subtypes of heart failure with preserved ejection fraction defined by machine learning A systematic review focused on defining high risk phenogroups

Simon W. Rabkin

487-518
Molecular mechanisms linking stress and insulin resistance

Habib Yaribeygi, Mina Maleki, Alexandra E. Butler, Tannaz Jamialahmadi, Amirhossein Sahebkar

317-334
“Nano-ghosts”: Risk assessment of submicron-sized particles in food biased towards fictional “nano”

Hanspeter Naegeli, Corina Gsell

279-299
LOX-1: Implications in atherosclerosis and myocardial ischemia

Tanya Sharma, Francesco Romeo, Jawahar L. Mehta

273-278
Prognostic significance and therapeutic potentials of immune checkpoints in osteosarcoma

Vafa Meftahpour, Ali Aghebati-Maleki, Ali Fotouhi, Elham Safarzadeh, Leili Aghebati-Maleki

250-268
The effects of low-toxic herbicide Roundup and glyphosate on mitochondria

Olha M. Strilbytska, Sviatoslav A. Tsiumpala, Ivanna I. Kozachyshyn, Tetiana Strutynska, Nadia Burdyliuk, Volodymyr Lushchak, Oleh Lushchak

183-196
Epidemiology and biology of early onset colorectal cancer

Anand Venugopal, John M. Carethers

162-182
Potential dual inhibitors of PCSK-9 and HMG-R from natural sources in cardiovascular risk management

Mohd Waiz, Sahir Sultan Alvi, M. Salman Khan

47-76
Large-scale comparative review and assessment of computational methods for phage virion proteins identification

Muhammad Kabir, Chanin Nantasenamat, Sakawrat Kanthawong, Phasit Charoenkwan, Watshara Shoombuatong

11-29

Case reports

Clinical presentation vs endoscopy for an early diagnosis of eosinophilic esophagitis a case report

Michele Di Stefano, Giacomo Grandi, Vera Bonaso, Elisabetta Pagani, Gino Roberto Corazza, Antonio Di Sabatino

651-655
Use of intranasal esketamine in a girl with treatment-resistant depression and autism spectrum disorders a case report

Miriam Olivola, Vincenzo Arienti, Nicola Bassetti, Serena Civardi, Natascia Brondino

540-543

Letters to the editor

Comment to the Letter to the Editor entitled “Lithium in drinking water and suicide risk” by Tomoyuki Kawada

Antonina Luca, Maria Luca

1066-1067
- Article - PDF
Recent insights into the biological functions of baicalin

Priscilla Nadalin, Jae Kwang Kim, Tae Won Kim, Sang Un Park

1019-1027
- Article - PDF
Delayed skin reactions after the second dose of mRNA vaccines against SARS-CoV-2

Paulo Ricardo Martins-Filho, Martha Débora Lira Tenório

1015-1018
- Article - PDF
Interventions on soy isoflavone molecules to improve their therapeutic potential for prostate cancer treatment

Vladimir Ajdžanović, Branka Šošić-Jurjević, Vesna Vodnik, Branko Filipović

941-947
- Article - PDF
Need to focus on inhibitory activity of benzimidazole analogues against indolamine 2,3-dioxygenase-1 (IDO-1)

Akshansh Sharma, Rajiv Tonk, Ravi Shekhar, Sushil Dohare, Deepak Kumar

904-905
- Article - PDF
Current update on the protective effect of epicatechin in neurodegenerative diseases

Riya Thapa, Gaurav Gupta, Piyush Dave, Santosh Kumar Singh, Abhay Raizaday, Waleed Hassan Almalki, Govind Vyas, Sachin Kumar Singh, Kamal Dua, Yogendra Singh

897-903
- Article - PDF
Introducing a new index for selecting genetic polymorphisms for association studies

Nafiseh Omidpanah, Mostafa Saadat

814-817
- Article - PDF
A revolution in health: Opportunities and challenges of the Metaverse

Milad Ahmadi Marzaleh, Mahmoudreza Peyravi, Fatemeh Shaygani

791-792
- Article - PDF
What are risk factors for COVID-19 vaccine breakthrough infections in patients with previous history of bariatric surgery?

Gerardo Sarno, Pietro Calabrese, Luigi Schiavo, Francesco Izzo, Vincenzo Pilone

786-790
- Article - PDF
Current update on anticancer effects of icariin A journey of the last ten years

Mukta Gupta, Yachana Mishra, Vijay Mishra, Murtaza M. Tambuwala

680-686
HDAC11: A novel inflammatory biomarker in Huntington’s disease

Vishal Kumar, Simranjit Kaur, Lakshay Kapil, Charan Singh, Arti Singh

647-650
Poorer and more densely populated regions have lower vaccination capability against COVID-19

Paulo Ricardo Martins-Filho, Ricardo Ruan Rocha Santana, Victor Santana Santos, Lorena G. Barberia

621-622
Current update on the protective effect of naringin in inflammatory lung diseases

Gaurav Gupta, Waleed Hassan Almalki, Imran Kazmi, Neeraj Kumar Fuloria, Shivkanya Fuloria, Vetriselvan Subramaniyan, Mahendran Sekar, Sachin Kumar Singh, Dinesh Kumar Chellappan, Kamal Dua

573-579
Lithium in drinking water and suicide risk

Tomoyuki Kawada

571-572
Toll-like receptors, innate immune system, and lung diseases a vital trilateral association

Vyoma K. Patel, Keshav R. Paudel, Shakti D. Shukla, Gang Liu, Brian G. Oliver, Philip M. Hansbro, Kamal Dua

519-523
Recent insights into the biological and pharmacological activity of lycopene

Jae Kwang Kim, Sang Un Park

415-425
Metabolic syndrome in childhood cancer survivors

Amena Firoz, Muhammad Haris

380-386
Preventive role of Sapindus species in different neurological and metabolic disorders

Sarita Rawat, Gaurav Gupta, Anurag Mishra, Sachchidanand Pathak, Lakshmi Thangavelu, Sachin Kumar Singh, Niraj Kumar Jha, Deepak Kumar, Poonam Negi, Avvaru Praveen Kumar, Dinesh Kumar Chellappan, Kamal Dua

354-359
- Article - PDF
Seroprevalence of SARS-CoV-2 antibodies in radio and television workers

Paulo Ricardo Martins-Filho, Danilo Nobre da Silva, Danillo Menezes dos Santos, Márcia Santos Rezende, Jessica Paloma Rosa Silva, Josafá Bonifácio da Silva Neto, Dulce Marta Schimieguel, Lucindo José Quintans-Júnior, Jullyana de Souza Siqueira Quintans, Paula Santos Nunes, Adriano Antunes de Souza Araújo

269-272

Vol. 21 (2022)

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Review articles

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